Best Research Institute El Monte Near Me

4worldlovers: As a leading pediatric academic medical center, research is a vital component of Children’s Hospital Los Angeles. Our overarching aim is to foster innovative research to improve the health and wellness of children and ensure the delivery of culturally competent care for diverse pediatric populations.

Every day, our expansive research community works to accelerate life-changing discoveries through a combination of basic, clinical and translational research studies focused on targeting new and better ways to prevent, diagnose and treat childhood diseases.

All research at the hospital happens under the auspices of The Saban Research Institute of Children’s Hospital Los Angeles, which is one of the largest and most productive pediatric research facilities in the United States. Established in 1992, The Children’s Hospital Research Institute became The Saban Research Institute in 2003 following a $40 million gift in support of pediatric research made by Cheryl Saban, PhD, Haim Saban and the Saban Family Foundation.

Research is performed across the hospital’s Sunset Campus within bench laboratories, dedicated clinical research space (including a clinical trials unit), in our inpatient and outpatient clinics, as well as in the surrounding community.

Investigators at The Saban Research Institute provide opportunities for families and communities to participate in research as our partners, joining us in tackling the most pressing challenges to pediatric health that can be addressed by discovery science.

Children’s Hospital Los Angeles is a premiere destination to host clinical research studies. Please refer to the downloadable PDF for more information.

The Institute is organized around four major research themes designed to promote collaboration and innovation in addressing pediatric health challenges:

Best Starts to Life aims to identify the earliest risk factors, address the impact of health and community disparities, and to deploy science-based interventions—from fetal through early childhood development—to improve the lives of all children.

From Discovery to Pediatric Care Innovation aims to transform knowledge gleaned from today’s clinical care into new and innovative approaches for tomorrow.

Pediatric Disease Models and Mechanisms aims to discover the underlying causes of pediatric disease—from genes to environmental factors—as a means to develop novel interventions and cures.

Personalized Prevention and Care aims to develop an understanding of each child down to the cellular level so that early and effective intervention can provide for a lifetime of sound health and well-being.

The Saban Research Institute of Children’s Hospital Los Angeles maintains strong scientific and strategic affiliations with the University of Southern California (USC) and the Keck School of Medicine of USC, where CHLA physicians and scientists hold faculty appointments. The Institute’s 392 principal investigators are involved in collaborative projects with academic institutions throughout the U.S. and abroad. The Saban Research Institute consistently ranks in the top 10 children’s hospitals for funding from the National Institutes of Health. In fiscal year 2022, CHLA received $51 million in National Institutes of Health (NIH) funding and $111.9 million in total extramural funding

The Saban Research Institute’s investigators—clinician-scientists, research scientists and health care professionals—work with and mentor the next generation of pediatric innovators. Our training programs include clinical and postdoctoral fellows, graduate students, medical students, undergraduates and high school students. Support is provided through the Training, Education, Career Planning and Development office that promotes the success of Children’s Hospital Los Angeles investigators and trainees through intramural funding programs and by providing opportunities for training, mentoring and collaboration.

At CHLA, Institutes are typically a combination of clinical activities and research. Research Centers and Programs are interdisciplinary with faculty investigators who are members of different divisions and departments at CHLA.

Cancer and Blood Disease Institute (Alan Wayne, MD, and Jim Amatruda, MD, PhD)

Center for Personalized Medicine (Alex Judkins, MD, and Jackie Biegel, PhD)

The Saban Research Building and Smith Research Tower provide more than 150,000 square feet of bench laboratory space dedicated to research. The first floor of The Saban Research Building also provides dedicated space to support on-site behavioral and psychological assessments of subjects and their accompanying families participating in clinical research studies.

Our scientists have access to advanced technologies, infrastructure, and data science and analyses through shared core facilities. Many of the research core facilities have pilot funding programs to provide investigators with opportunities to acquire necessary preliminary experimental data to demonstrate technical and analytical capabilities.

4worldlovers:
Every department of Beckman Research Institute of City of Hope includes internationally acclaimed scientists and support staff who are among the best in their fields, pursuing a diverse range of research. The result is a history of breakthrough innovations helping patients globally, with even more to come in the years ahead.


Studies here advance translational medicine through breakthroughs in cancer biology using animal models, biomedical informatics, chemical biology and genomic approaches.

Studies here are focused on discovering the fundamental mechanisms of DNA replication and DNA damage repair during cell growth.

Beckman Research Institute of City of Hope leads the world in biomedical research, and whenever possible, our researchers use alternative methods to animal models, such as cell and tissue culture and computer simulation. However, in many circumstances, the responsible and limited use of animals is necessary for the discovery of new therapies.

The Department of Computational and Quantitative Medicine within the Beckman Research Institute was created to integrate various aspects of computational medicine. It is charged with building cross-disciplinary collaborations and developing better diagnostic tools, improved personalized therapies, and more efficient clinical trials, consistent with the mission of City of Hope.

The focus of the Department of Hematologic Malignancies Translational Science is to improve the understanding of leukemia stem cells in order to develop cures for leukemia and other hematologic malignancies.

Researchers in the Department of Immuno-Oncology are pioneering medical science that harnesses the power of the body’s own immune system to fight cancer. They intend to move immunotherapy forward to the front lines by making it a highly effective primary treatment option, capable of producing more powerful, less toxic cures.

The molecular diagnostics and experimental therapeutics research program has a broad research focus on understanding the molecular pathogenesis of human gastrointestinal cancers and its relationship to early detection of cancer, cancer prevention and cancer therapeutics.

Researchers across multiple divisions are targeting what causes cancer, how to prevent people from getting cancer, and how to improve the quality of life of cancer survivors.

The mission of the Department of Stem Cell Biology & Regenerative Medicine is to harness the power of stem cells to battle cancer, aging, and tissue degeneration. Research in the department spans from understanding the fundamental processes of organs’ development to the development of new therapies and clinical trials.

The Department of Systems Biology aims to understand the complex biological systems involved in signal transduction and in the transcriptional, epigenetic and metabolic regulation of hematological malignancies, leukemia and lymphoma.

Beckman Research Institute of City of Hope was the first of five Beckman Institutes to be founded, and has held a National Cancer Institute Cancer Center Support Grant for over 30 years.

Encompassing over 60 years of expertise in basic science, Beckman Research Institute also houses research done at City of Hope prior to the establishment of the institute by Arnold and Mabel Beckman in 1983.

Its world-renowned faculty and investigators are revolutionizing the treatment of life-threatening diseases, creating miracles of medical science.

Research areas include diabetes progression and treatment, immunology and imaging, interfering RNAs and HIV treatment, total synthesis of complex and therapeutic natural products, mechanisms of drug action, neurogenesis, stem cell therapy, DNA repair and radiation, and the immunobiology of viral infection.

Investigating the biology, biological chemistry, and pathology of cancer and diabetes, our researchers have also explored the emerging links between the diseases. By identifying opportunities at the cellular and molecular level, they continue developing breakthrough approaches for predicting, preventing, diagnosing, treating and curing these and other serious diseases.

Through constant collaboration and interaction between Beckman Research Institute programs, and those found within City of Hope's NCI-designated comprehensive cancer center, our researchers and clinicians are maximizing the benefits our research is able to deliver.

Recognized nationwide for its innovative biomedical research, the institute is home to some of the most tenacious and creative minds in science.

Beckman Research Institute houses the Irell & Manella Graduate School of Biological Sciences. The school offers M.S. degree in translational medicine and Ph.D. degree in biological sciences.